Saturday, December 8, 2007

Article 2.

  • a study of the tapeworms Taenia solium, Taenia ovis, and Taenia saginata
  • all are capable of infecting humans
  • T. solium infects pigs
  • dogs are the definitive host of T. ovis and humans are for T. saginata.
  • article examined the need for a vaccines
  • vaccines against cysticercosis already in existance
  • these vaccines are for the tapeworms T. sagunata in cattle and T. ovis in sheep
  • it is possible these vaccines would be just as effective for vaccination pigs against infections of T. solium due to homologues protein coding
  • vaccination against hydatid dissease is done in sheep
  • vaccines were created using recombinant DNA technology
  • genes encoding different antigens were cloned
  • the results were used to produce the vaccines
  • it was found that the combination of tow recombinant protein into a single vaccine gave a highly effective result
  • the benefits of livestock vaccination to human morbidity and mortality are indirect
  • a more direct approach would be to use protective vaccines against cysticercosis and hydatid disease in humans
  • discussions have started to begin human trials

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